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Tetracaine HCl is a potent local anaesthetic and a channel function allosteric inhibitor.Target: Calcium ChannelTetracaine hydrochloride is a calcium channel protein inhibitor and blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum. Tetracaine is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia. Tetracaine is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely
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Chemical & Physical Properties
Boiling Point 389.4ºC at 760 mmHg
Melting Point 149°C
Molecular Formula C15H25ClN2O2
Molecular Weight 300.824
Flash Point 189.3ºC
Exact Mass 300.160461
Vapour Pressure 2.87E-06mmHg at 25°C
Storage condition Refrigerator